DESCRIPTION

Erlonat 150mg tablet has Erlonat 150mg active ingredient Erlotinib,Erlonat 150mg tablet used to treat non-small Erlonat 150mg cell lung cancer, pancreatic cancer and Erlonat 150mg tablet other various types of cancer. Erlonat 150mg is pharmacologically Erlonat 150mg categorized asErlonat 150mg tablet tyrosine kinase inhibitor, Erlonat 150mg acts on epidermal growth factor receptor.

Erlonat 150mg tablets are prescription Erlonat 150mg medicine,Erlonat 150mg tablet used only by the patients who have Erlonat 150mg tablet valid prescription

INDICATION AND USAGE

Erlonat 150mg is primarily Erlonat 150mg indicated for; Erlonat 150mg tablet Non small cell lung cancer: Erlonat 150mg tablet is considered as second, Erlonat 150mg tabletmaintenance or Erlonat 150mg greater line treatment in NSCLC. It is used after failure of some Erlonat 150mgchemotherapy regimens. Erlonat is involved in the Erlonat 150mg tablettreatmentErlonat 150mg tablet of non-small cell lung cancer patients whose cancer cells Erlonat 150mg containing epidermal growth Erlonat 150mg tabletfactor receptors on their surface. Erlonat 150mg is not used in combination with Erlonat 150mg tabletplatinum based compounds. In pancreatic carcinoma: In metastatic stage, Erlonat is used in Erlonat 150mg tablet combination with gemcitabine. In this Erlonat 150mg condition Erlonat 150mg tablet Erlonat is involved as first line treatment.

WARNING

Some of the adverse Erlonat 150mg tableteffects occur Erlonat 150mg tablet price in india while treating with Erlonat 150mg tablets; Interstitial lung disease Renal impairment Hepatic toxicity with liver Erlonat 150mgfailure Erlonat 150mg tabletGastrointestinal perforation Bullous & exfoliative skin disorders CerebrovascularErlonat 150mg tabletdisordersErlonat 150mg tablet Hemolytic Erlonat 150mganemia &Erlonat 150mg tablet thrombocytopenia Hemorrhage Ocular disorders Embryo fetal toxicity

ERLONAT PHARMACOLOGY

Erlonat has pharmacological effects like Erlonat 150mg tabletanti-tumor activity, Erlonat 150mg tabletwhich expels its action by prohibiting Erlonat 150mg tabletthe intracellular phosphorylation Erlonat 150mg of tyrosine kinase related with epidermal growth Erlonat 150mg factor receptor. Erlonat 150mg tabletThis EGFR is occurs on the surface Erlonat 150mg of the tumor cells. Thus results as prohibition leads to intercede with signal transduction and lead to cell lyses.

ERLONAT ADME PROPERTY

ABSORPTION

The peak plasma concentration time reaches at 4 hours after drug intake After drug intake, the Erlonat 150mg tabletoral bioavailability of Erlotinib occurs as 60%, whereas a meal increases its bioavailability to Erlonat 150mg tablet100%. The Erlotinib Erlonat 150mg tablet 1 solubility is depends upon pH level. The reduction in Erlonat 150mg solubility causes elevation of the pH levels. SmokingErlonat 150mg tablet should be Erlonat 150mg avoided during the Erlonat 150mg tablettreatment with Erlonat 150mg , causes decreasing the exposure of Erlotinib.

DISTRIBUTION

Volume of Erlonat 150mg distribution Erlonat 150mg tablet price in india of Erlotinib is Erlonat 150mg tablet 232L Human protein binding to Erlotinib 150mg tablet is occurs as 93%.

METABOLISM

The Erlonat 150mg tablet price in india metabolism of ErlotinibErlonat 150mg tablet is occurs by CYP3A4

ELIMINATION

The route of Erlonat 150mg elimination of Erlonat 150mg tablet Erlotinib metabolites occurs via; Feces: Erlonat 150mg 83%; urine:Erlonat 150mg tablet 8% The terminal half life period of Erlotinib is 36.2 hours.

PRODUCT DETAILS

Brand : Erlonat

Ingredients : Erlotinib

Strength : 150mg

Manufactured : Natco

Package : 30 Tablets

DOSAGE ADMINISTRATION

DOSAGE MANAGEMENT

In NSCLC: The Erlonat 150mg tablet price in india recommendedErlonat 150mg tablet dosage is 150mg should be taken as a single dose by administering on an empty Erlonat 150mg stomach. In pancreatic cancer: The usual Erlonat 150mg dosage of Erlonat 150mg tablet Erlonat is Erlonat 150mg tablet100mg should Erlonat 150mg tablet be taken as a singleErlonat 150mg tablet price in india dose by administering on an empty stomach by combining with gemcitabine. Erlonat 150mg tabletDose alteration: Erlonat 150mg tabletIn pulmonary toxicity: Interstitial lung disease,Erlonat 150mg tablet price in india pulmonary failure: Erlonat 150mg tablet Discontinue the Erlonat therapy In severe hepatic failure: Stop the therapy permanently

In renal impairment:Erlonat 150mg tablet Discontinue the Erlonat 150mgtherapy permanently Erlonat 150mg In gastrointestinal perforation and severe diarrhea: Stop the therapy In severe Erlonat 150mg tablet Bullous and exfoliative skinErlonat 150mg tablet disorders: Discontinue theErlonat 150mg tablet therapy Erlonat 150mg tablet price in india and provide supportive measures In corneal perforation, therapy should be Erlonat 150mg discontinuing permanently. Erlonat 150mg tablet Avoid concomitant use of Erlonat with CYP3A4 strong inhibitors, CYP3A4 strong inducers, Erlonat 150mg tablet price in india cigarette smoking, gastric regulators etc.

SIDE EFFECTS

SOME SERIOUS ADVERSE EFFECT

Renal failure Erlonat 150mg Liver toxicity Erlonat 150mg tablet price in india with failure Erlonat 150mg Gastrointestinal perforations Ocular disorders Erlonat 150mg tablet Hemorrhage Bullous &Erlonat 150mg tablet price in india exfoliative skin Erlonat 150mg disorders Cerebrovascular disorders Hemolytic Erlonat 150mg tablet anemia & thrombocytopenia

Rash Diarrhea Cough Erlonat 150mg tablet Dyspnea Dry skin Back pain Conjunctivitis Erlonat 150mg tablet price in india Mucosal inflammation Erlonat 150mg tablet Pruritus Paronychia Chest pain, Erlonat 150mg tabletarthralgia Musculoskeletal pain Myopathy like rhabdomyolysis while combining with lipid lowering drugs

DRUG INTERCTION

CYP3A4 INHIBITORS:

Concomitant use of Erlonat 150mg tablet with CYP3A4 inhibitors like (boceprevir, clarithromycin, conivaptan, indinavir, itraconazole, ketaconazole, Erlonat 150mg lopinavir/ritonavir, Erlonat 150mg tabletnefazodone, nelfinavir, posaconazole, Erlonat 150mg ritonavir, saquinavir, telithromycin, Erlonat 150mg tablet price in india voriconazole, Erlonat 150mg tablet price in india grapefruit Erlonat 150mg tablet or grapefruit juice) causes increasingErlonat 150mg the exposure of Erlotinib. This result as increase in risk of adverse effects related to Erlonat .

IN CYP3A4 INDUCERS:

In combination of Erlonat Erlonat 150mg with Erlonat 150mg tabletCYP3A4 inducers likeErlonat 150mg tablet price in india anti-convulsants, Erlonat 150mg tablet price in india rifampin, rifampicin, st Johns wort etc Erlonat 150mg tablet price in india causes decreasing the exposure of Erlotinib. Erlonat 150mg tabletThus results as decrease in therapeutic effect of Erlonat .

CYP1A2 INDUCERS & CIGARETTE SMOKING:

Both are Erlonat 150mg tablet price in india decreasing the exposure Erlonat 150mg of Erlotinib, while concomitant with Erlonat .

GASTRIC REGULATORS:

While Erlonat 150mg concomitant with gastric Erlonat 150mg tabletregulators like proton pump inhibitors, H2 receptors antagonist or antacids, causes depletion Erlonat 150mg tablet price in india of Erlotinib exposure Erlonat 150mg tablet leads to loss of therapeutic effect of Erlotinib.

ANTICOAGULANTS:

In Erlonat 150mg combination of Erlonat Erlonat 150mg tabletwith warfarin, causes increasing international Erlonat 150mg tablet price in india normalized ratio & bleeding Erlonat 150mg tablet price in indiaadverse reactions. To avoid this problem, monitor Erlonat 150mg tablet the prothrombin time frequently.

Email id :millionhealthpharmaceuticals@gmail.com

Contact us :+91–9940472902

Website :https://millionpharma.com/erlonat.php

keywords: Erlonat 150mg tablet, Erlonat 150mg,Erlonat 150mg tablet price in india